Scientific context:
The ERC Synergy NanoBubbles project is led by researchers from the Universities of Sorbonne Paris Nord, Maastricht, Grenoble-Alpes and Radboud, in collaboration with researchers from the CNRS, the University of Twente, IRIT and Ecole des Ponts (https://nanobubbles.hypotheses.org/). The project focuses on how, when and why science fails to correct itself. To understand how the correction of science works or fails, the NanoBubbles project combines approaches from the natural sciences (physics, chemistry, biology), engineering (natural language processing) and humanities and social sciences (linguistics, sociology, philosophy and history of science).
Within that project sits the first replication initiative in nanobioscience, where we also pioneer in this field open science approaches (protocol, data and sample sharing, registered reports, etc). The scientific focus is the paradox of endosomal escape, i.e. on articles that report the use of nanoparticles as sensors of cytosolic intracellular targets in spite of the probable endosomal entrapment of those probes after cell uptake. We have recently completed the first replication and are currently completing the experimental phase of the second replication.
The NanoBubbles replication team is hosted in Bobigny in team 4 of the Laboratory for Vascular Translational Science (https://lvts.fr/).
Objective:
We are seeking to recruit a chemist with expertise in nanoparticle synthesis, functionalisation and characterisation to join the replication team. The chemist will work with a biologist to contribute to the replication of further articles. The objective is to shed light on the reproducibility of those articles, help solve the paradox of endosomal escape and contribute to the improvement of methods and approaches in this field. Given the nature of this project, we are looking for a meticulous person motivated to adhere to, and even develop, rigorous scientific standards. That person should also be enthusiastic about communicating with colleagues of very different disciplines.
Qualifications we require: PhD in chemistry or material sciences
Experience:
- Experience in nanoparticle synthesis and characterisation.
- Experience in interactions of nanoparticles with biological systems.
- Previous post-doctoral experience is valued but not mandatory.
- Experience with handling and assembly of oligonucleotides is valued but not mandatory.
Field of research: Bionanoscience, chemistry
Skills: Nanoparticle synthesis, Nanoparticle functionalisation, Nanoparticle characterization, Oligonucleotides handling
Where to apply: https://rubis.univ-spn.fr/offres/voir/209
Additional Information:
Contacts:
nikolina.rakotoarivonyunivparis13.fr
Application Deadline:
20 Feb 2026 – 00:00 (UTC)
Type of Contract: Temporary
Job Status: Full-time
Offer Starting Date: 20 April 2026
This job is funded through the EU Research Framework Programme
End of contract: 28 may 2027
Work Location:
Université Sorbonne Paris Nord
Laboratoire de Recherche Vasculaire Translationnelle (Laboratory for Vascular Translational Science)
Site de Bobigny, 1 rue Chablis, 93000 BOBIGNY